ROS are beneficial for biosystem presenting as signalling molecules and enhancing immunologic defence. However, they also have harmful effects such as causing tissue and organ damages. The results are controversial in studies focusing on ROS and ROS-related diseases by regulating ROS with inhibitors or promotors.

Reactive oxygen species (ROS) are involved in many important cellular activities including gene transcription, signaling transduction, and immune response. Common ROS include hydroxyl radical (•OH), superoxide (O 2•–) and hydrogen peroxide …

During the past decades, it became obvious that reactive oxygen species (ROS) exert a multitude of biological effects covering a wide spectrum that ranges from physiological regulatory functions to damaging alterations participating in the pathogenesis of increasing number of diseases.

Nov 10, 2015 · To target redox-dependent diseases safely and effectively, physiological ROS sources that are relevant for signaling need to remain untouched, while disease-triggering ROS should be effectively reduced.

Dec 12, 2005 · Reactive oxygen species (ROS)—superoxide radicals, hydrogen peroxide and other related compounds—are produced continuously in most tissues. ROS can react with many different macromolecules and thereby cause damage to, …

May 17, 2018 · The overproduction of reactive oxygen species (ROS) has been implicated in the development of various chronic and degenerative diseases such as cancer, respiratory, neurodegenerative, and digestive diseases.

Jul 7, 2014 · For years, accumulating evidence suggested that reactive oxygen species (ROS) increase in various disease states. What naturally flowed from these observations was the seemingly obvious...

Aug 17, 2012 · Upon reaction with electrons, oxygen is transformed into reactive oxygen species (ROS). It has long been known that ROS can destroy bacteria and destroy human cells, but research in recent decades has highlighted new roles for ROS in health and disease.

With the relentless effort of studies, researchers have explored the role of ROS in biosystem and various diseases. ROS are beneficial for biosystem presenting as signalling molecules and enhancing immunologic defence. However, they also have harmful effects such as causing tissue and organ damages.

Reactive oxygen species (ROS) are well-known for playing a dual role as destructive and constructive species. Indeed, ROS are engaged in many redox-governing activities of the cells for the preservation of cellular homeostasis.