SIRT1, a protein deacetylase, known to be protective in inhibiting oxidative stress and inflammation within the vessel wall, has been shown as a possible key player in modulating …

Sidgwick, G.P., Weston, R., Mahmoud, A.M., Schiro, A., Serracino-Inglott, F., Tandel, S.M., Skeoch, S., Bruce, I.N., Jones, A.M., Alexander, M.Y., Wilkinson, F.L. (2024) 'Novel …

May 13, 2020 · Immunohistochemistry revealed decreased SIRT1 and increased DNA damage marker expression in diabetic calcified arteries compared to non-diabetic and non-calcified …

Ferdinand Serracino Inglott2, M. Yvonne Alexander1, and Ria Weston 1* 1Department of Life Science, ... Tel: þ44 161 247 1142, E-mail: [email protected] VC The Author(s) 2020. …

Ria Weston currently works as a Senior Lecturer at the Centre for Bioscience, Manchester Metropolitan University. [...] Post-translational modification of proteins by poly (ADP …

SIRT1, a protein deacetylase, known to be protective in inhibiting oxidative stress and inflammation within the vessel wall, has been shown as a possible key player in modulating …

Sep 1, 2004 · Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor. Loss of SIRT1 in diabetes accelerates DNA …

May 13, 2020 · Aims Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress …

May 13, 2020 · Bartoli-Leonard, F., Wilkinson, F. L., Schiro, A., Inglott, F. S., Alexander, M. Y., & Weston, R. (2021). Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular …

Showcase your career and increase your impact by adding your brief bio now. Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification. This researcher does not …