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What does PICO do? PICO provides suction known as Negative pressure wound therapy (NPWT) which draws out excess fluid from a wound and protects the incision or wound. How does PICO work? PICO consists of an NPWT pump connected to an absorbent gentle adhesive dressing.

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Oct 14, 2020 · As developed by Junqueira and colleagues in 1979, specific staining by Picrosirius red is one of the most important stains to study collagen networks in different tissues.

VitroView™ Picro-Sirius Red Stain Kit is designed for stain of collagen I and III fibers. The Sirius Red stain may be viewed using standard light microscopy or polarized light resulting in birefringence of the collagen fibers to distinguish between type I and type III.

Test your sirius red on sections of muscle, brain and kidney before using it for research or diagnosis. In normal kidney the glomerular basement membranes should be red but not birefringent.

Jan 26, 2024 · To the best of my knowledge, most users of picro-sirius red are doing research that exploits the enhancement by sirius red of the birefringence of collagen fibres, which is largely due to co-aligned molecules of Type I collagen. It is also used to stain amyloid.

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Picrosirius red (PSR) staining viewed under polarized light microscopy is the standard method to evaluate the organization of collagen fibers in tissues. It is also used to distinguish between type I and type III collagen in tissue sections.