Myristicin is a naturally occurring compound (a benzodioxole) found in common herbs and spices, such as nutmeg. [ 1 ] [ 2 ] It is an insecticide , and has been shown to enhance the effectiveness of other insecticides.

Aug 31, 2018 · The chemical responsible for the “high” caused by nutmeg is known as myristicin. Myristicin is a compound found naturally in the essential oils of certain plants, such as parsley, dill, and...

Myristicin is a naturally occurring insecticide and acaricide with possible neurotoxic effects on dopaminergic neurons[citation needed]. It has hallucinogenic properties at doses much higher than used in cooking. Myristicin is a weak inhibitor of monoamine oxidase.

Myristicin is a naturally-occurring deliriant substance of the phenylpropene class. It is present in small amounts in the essential oil of nutmeg and, to a lesser extent, in other spices such as parsley and dill.[1]

Myristicin is a molecule that is still poorly studied and is still not used in therapy, but the few available data point to a promising therapeutic potential.

May 23, 2023 · This review summarizes the biological activities of myristicin and myristicin-rich plants, toxicological effects along with its bioavailability, and metabolism. In addition, their traditional uses and their role as ecological remedy in plants protection has been reviewed.

Just recently in 2019, NTP characterized the mutagenic potential of myristicin. Myristicin was not mutagenic in S. typhimurium with or without metabolic activation. In addition, a micronucleus test was integrated in the subchronic toxicity study in which myristicin (0, 10, 30, 100, 300, or 600 mg/kg bw; 5 days/week) was administered via gavage ...

Myristicin is an analogue of MMDA and MDMA and a moderate monoamine oxidase inhibitor. It can be metabolised to form amphetamine derivatives, which bind with 5-HT 2A receptors and act as 5-HT agonists.

Sep 29, 2021 · The purpose of this review article is to discuss data published in the last 10 years at Pubmed, Lilacs and Scielo databases, reporting beneficial effects, toxicity and promising data of myristicin for its future use in medicine.

Sep 29, 2021 · In this context, myristicin, a substance of natural origin, has shown several promising activities in a large number of in vitro and in vivo studies carried out.