A DNA model that unifies information across the molecular, systems, and genome scales could learn from large genomic regions to capture systems-wide interactions and enable the design …

A molecular model is a physical model of an atomistic system that represents molecules and their processes. They play an important role in understanding chemistry and generating and testing …

Nov 15, 2024 · We present Evo, a long-context genomic foundation model with a frontier architecture trained on millions of prokaryotic and phage genomes, and report scaling laws on …

1 day ago · The development of multimodal foundation models, pretrained on diverse omics datasets, to unravel the intricate complexities of molecular cell biology is envisioned.

Molecular models can be any physical representation of molecular configuration assigned to molecular objects that are constructed to understand and explain measurable characteristics …

Molecular modelling methods are used routinely to investigate the structure, dynamics, surface properties, and thermodynamics of inorganic, biological, and polymeric systems. A large …

We summarize the foundation models developed based on RNA sequence data, DNA sequence data, protein sequence data, single-cell transcriptome data, and spatial transcriptome data …

The rapid advent of high-throughput omics technologies has created an exponential growth in biological data, often outpacing our ability to derive molecular insights. Large-language models …

Mar 13, 2025 · Generative models have gained widespread attention in recent years due to their inverse design capabilities and their potential to accelerate the molecular design and discovery …

Apr 3, 2025 · Proteins and protein complexes form adaptable networks that regulate essential biochemical pathways and define cell phenotypes through dynamic mechanisms and …