Tie-Chi LEI, Head of Department | Cited by 1,716 | | Read 65 publications | Contact Tie-Chi LEI

Li LC, Lei TC, Xing F. Bimatoprost promotes hair growth of reconstructed hair follicles in mice through activation of the Wnt/β-catenin signaling pathway. Zhonghua Yi Xue Za Zhi. 2021 Jun 1;101(20):1529-1534.

Expression of matrix metalloproteinase-1 (MMP-1), tyrosinase, fibrillin and tropoelastin was detected by reverse transcription-quantitative PCR, western blotting and immunofluorescence. The present results showed that PRP treatment improved skin quality in the participants.

Conclusion: Our results suggest the roles of IL8-CXCR2 activation in promoting MC proliferation and of BD3 upregulation in reducing melanogenesis. These findings have been implicated in …

Jul 5, 2023 · Recent studies have shown that senescent dermal fibroblasts resulting from chronic solar ultraviolet radiation (UVR) secrete soluble senescent-associated secretory phenotype factors, such as pro-inflammatory cytokines, angiogenic factors, and matrix metalloproteinases (MMPs), that incite melanocytes to drive epidermal hyperpigmentation in melasm...

Tie-Chi LEI, M.D. & Ph.D. Professor of Dermatology, Tutor for doctoral candidates. He now is the chair of Dermatology Department, Renmin Hospital of Wuhan University (RHWU), Wuhan, China. He was a post-doctoral fellow at the National Institutes of Health (NIH, Bethesda, USA) from 1999 to …

Jul 5, 2023 · Jing Wan 1 , Zhikai Liao, Bingqi Dong, Shan Jiang, Tiechi Lei Affiliation 1 Department of Dermatology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China.

Involvement of interferon γ-producing mast cells in immune responses against melanocytes in vitiligo requires MrgX2 activation.

Jan 13, 2025 · Dong Bingqi, Lei Tiechi. Resident Cutaneous Memory T Cells in the Pathogenesis and Progression of Vitiligo Lesions [J]. Medical Research Journal, 2024, 53(03): 177-180.

Jul 15, 2024 · Li Qianwen, Liao Zhikai, Le Yue, Duan Bolin, Geng Mengmeng, Lei Tiechi. The antioxidant Tempol inhibits pigment loss in tail skin of a mouse model of immune-induced vitiligo under oxidative stress[J]. Chinese Journal of Dermatology, 2025, 58(2): 126-131.doi:10.35541/cjd.20240375