The Brent Lab is developing and applying computational methods for mapping gene regulation networks, modeling them quantitatively, and engineering new behaviors into them.

The Brent Lab is developing and applying mathematical and computational methods for mapping gene regulation networks, modeling them quantitatively, and synthesizing new network designs in living cells.

Brent A. Hanks, MD, PhD, is an Associate Professor with Tenure in the Department of Medicine and Department of Microbiology and Immunology at Lineberger Comprehensive Cancer Center at University of North Carolina.

P. Brent Ferrell, Jr., M.D. Assistant Professor of Medicine Research: Molecular investigations in myeloid disease Clinical: Myeloid malignancies, clinical trials, VA Tennessee Valley (Nashville)

We use diverse chemical and biological tools to elucidate new mechanisms related to cell death, metabolism, and disease. For example, we design small molecule inhibitors and activators of proteins using high resolution structural information and computational chemistry tools.

Brent R. Stockwell, Ph.D. is Chair of the Department of Biological Sciences and a Professor at Columbia University in the Departments of Biological Science and Chemistry. His research involves the discovery of small molecules that can be used to understand and treat cancer and neurodegeneration, with a focus on biochemical mechanisms governing ...

The Brent Lab Center for Genome Sciences & Systems Biology 4515 McKinley Ave., 4th floor, Room 4307 St. Louis, MO 63110 Tel: 314.286.0210 Fax: 314.935.7302 Email: brent[at]wustl.edu

The Brent lab is interested in how gene expression is regulated, how it affects phenotypes, and how it is affected by genetic variants. Our work includes fungi (baker's yeast and Cryptococcus neoformans, a fungal pathogen) and humans.

Brent joined the faculty of UCSF Department of Biopharmaceutical Sciences as an Adjunct Professor in 2000 and was named a Senior Scholar of the Ellison Medical Foundation in 2001. In July 2009, Roger joined Fred Hutchinson Cancer Research Center as a Full Member in the Basic Sciences Division.

We are using chemical and biological tools to study ferroptosis, a form of regulated cell death discovered in the Stockwell Lab. Ferroptosis is an iron-dependent form of oxidative, non-apoptotic cell death that is tightly linked to metabolism and disease.