An Io rune is a low-mid rune which can be socketed into equipment in Diablo II: Lord of Destruction. Io runes are somewhat rare, but their value tends closer to low runes, due to a lack of popular uses.

An Io Rune is a low tier rune that can be socketed into armor and weapons in Diablo 2: Lord of Destruction and Diablo 2 Resurrected. An Io Rune requires level 35 to use. When you socket an item with an Io Rune, you increase the level requirement to level 35, unless it was already higher.

Jun 24, 2021 · This is a searchable, filterable, sortable database of all Diablo 2 Resurrected Runewords. It shows the latest data from Resurrected v2.8 (where indicated), and otherwise uses data from Diablo 2 v1.14 LoD.

Nov 16, 2021 · A list of all the runes in Diablo 2 and the Horadric Cube recipe to convert them to a higher level rune. Note: Not all runes are worth upgrading to higher level, especially high level runes¹ mentioned by Hoost07 under this post

Io Rune is the last rune that can be dropped by Nightmare Countess; therefore, it is one of the hardest low runes to obtain. Farming: 25 Nightmare Countess Runs. Cubing: 14 Nightmare Countess Runs.

Apr 2, 2025 · Details of the Io rune and all the possible runewords for the Io rune.

Mar 7, 2011 · Here are the Io attributes: Look at the rune list for information on how to get the right runes. For weapons you'll want to find the best type of weapon possible, since that's what the bonus damage is based on. Same with Armor if you are after Defense and shields for …

Mar 6, 2023 · Io is a Rune in Diablo 2. Io can be applied to Socketed Items, by doing so it grants said item different properties depending on if the Socketed Item is a Weapon or a piece of Armor. Runes can also be used in some Horadric Cube's recipes.

Io Rune is a low rune used in the runewords White, Black, Cure, Temper, Ground, Hearth, Bulwark, Delirium, Metamorphosis, Dream (Helm), Dream (Shield), Memory, Pride, Obsession, Unbending Will. The Io Rune can also be used as ingredient for 2 different Horadric Cube recipes.

Hey, I’m Zathong and this guide is about Io rune in Diablo 2. Io grants item different properties depending on if the Socketed Item is a Weapon or a piece of Armor. Let’s just get into the details below!