Jan 31, 2024 · A diagonal ear lobe crease (DELC), or Frank’s sign, is a deep crease or wrinkle extending to the earlobe. Some studies suggest this indicates a greater risk for coronary artery disease, which...

Aug 13, 2014 · Does having an earlobe crease mean you're destined to have a serious heart condition? Director of Heart Disease explains the risks those with an earlobe crease should be aware of.

Frank's sign is a diagonal crease in the ear lobe extending from the tragus across the lobule to the rear edge of the auricle. [1] . The sign is named after Sanders T. Frank. [1] It has been hypothesised that Frank's sign is indicative of cardiovascular disease [2][3] and/or diabetes. [4] .

Jul 2, 2015 · Korkmaz L, A X011f Ac MTXK, Acar Z, et al. Earlobe Crease May Provide Predictive Information on Asymptomatic Peripheral Arterial Disease in Patients Clinically Free of Atherosclerotic Vascular Disease.

An ear lobe crease is, quite simply, a crease in your earlobe. Normally, the earlobe's surface is smooth and unwrinkled. But in 1973, Dr. Sanders T. Frank described a way that the texture of your earlobe could signify the presence of heart disease.

Nov 14, 2024 · Frank’s sign refers to a diagonal earlobe crease that can indicate underlying circulatory issues and is a surprisingly accurate predictor of coronary heart disease. Learn what causes Frank’s sign and discover natural and effective ways to support a healthy heart and vascular system.

The ear lobe crease (ELC) has been defined as a deep wrinkle that extends backwards from the tragus to the auricle. It has been proposed that ELC is a predictor of coronary artery disease (CAD). In this review, we consider the possible association ...

Jan 13, 2018 · A study in 1973 showed a connection between an ear crease and heart disease. Find out if a small mark on your ear could have anything to do with heart disease.

Apr 12, 2025 · According to Dr Frank, this type of earlobe fold was a physical sign that could indicate the presence of coronary artery disease. The cause of this sign is still unclear. In the 1980s, it was ...

Three types of ear creases have been described in the medical literature in association with several cardiovascular and metabolic disorders: diagonal earlobe creases (DELCs) (Frank’s sign), preauricular vertical creases, and paired ear creases of the helix (PECH).