Based on these data, we diagnosed Cogan syndrome (CS) after excluding syphilis, ANCA-associated vasculitis and other autoimmune diseases. With high-dose methylprednisolone (120 mg daily), his hearing and vision improved.

We present a case of atypical Cogan’s syndrome, distinguished by its onset following a COVID-19 infection and unusual features including ophthalmic conditions beyond keratitis and the development of neurological symptoms.

There is growing evidence that coronavirus disease 2019 (COVID-19) can lead to a dysregulation of the immune system with the development of autoimmune phenomena. The consequence of this immune dysregulation ranges from the production of autoantibodies to the onset of rheumatic autoimmune disease.

Aug 25, 2023 · Cogan syndrome is a rare multisystem autoimmune disease affecting the ocular and audiovestibular system with unknown pathogenesis. It occurs mainly in young white adults in the third decade of life as they present with interstitial keratitis and hearing loss.

Clin Rheumatol. 2023 Jun 4;1-2. doi: 10.1007/s10067-023-06642-4. Online ahead of print. 1 Department of Rheumatology and Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No.197 Ruijin Second Road, Shanghai, 200025, China. Keywords: COVID-19; Cogan syndrome; Vasculitis.

Sep 27, 2024 · We report a 28-year-old female who experienced decreased visual acuity and ocular redness one month after a COVID-19 infection, with ophthalmological signs linked to keratitis, uveitis and retinal vasculitis. Two weeks later, she developed vertigo, tinnitus, and sudden hearing loss, leading to a diagnosis of Cogan’s disease.

Sep 27, 2024 · Background: Cogan's syndrome is a rare autoimmune disorder characterized by ocular inflammation, vestibulocochlear dysfunction, and systemic vasculitis. Case presentation: We report a 28-year-old female who experienced decreased visual acuity and ocular redness one month after a COVID-19 infection, with ophthalmological signs linked to ...

Aug 21, 2024 · Cogan syndrome (CS) is a chronic inflammatory disorder that most commonly affects young adults. Clinical hallmarks are interstitial keratitis (IK) and vestibuloauditory dysfunction [ 1 ]. Associations between CS and systemic vasculitis, as well as aortitis, also exist [ …

According to the study, the effectiveness of the COVID 19 vaccine in terms of COVID-19-related hospitalization, admission to the intensive care unit, and death was 89.1%, 97.4%, and 99.0%, respectively.

Based on these data, we diagnosed Cogan syndrome (CS) after excluding syphilis, ANCA-associated vasculitis and other autoimmune diseases. With high-dose methylprednisolone (120 mg daily), his hearing and vision improved.