The moves by the Department of Health and Human Services represent a substantial shift in the government’s philosophy on transgender and nonbinary issues, toward one that rejects the idea that Americans can identify with a gender other than their sex at birth. The new information aligns with President Donald Trump’s executive orders on the subject.

Robert F. Kennedy Jr., a prominent vaccine critic, was confirmed Thursday by the U.S. Senate in a 52-48 vote to serve as the nation’s top health official.

Kennedy tried to hold out an olive branch to the researchers during his introductory remarks and pledged transparency.