A new study from King Abdullah University of Science and Technology (KAUST), published in Nature, captures the moment DNA ...

Using cutting-edge cryo-electron microscopy, the team of scientists were able to visualize a helicase enzyme (nature’s DNA unzipping machine) in the process of unwinding DNA. DNA helicases are ...

Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...

Nucleic acid unwinding is an essential step in many biomolecular processes. Researchers in this field recently met to examine progress and outstanding issues. Helicases are molecular motors that ...

Chromatin regulators help moderate gene expression, cell division, and DNA damage repair by unwinding and compacting DNA, changing which genes are exposed. "Genome structure controls many ...