One direct application of molecular testing is in the case of pregnancies in which two affected parents have the same or different autosomal dominant skeletal disorders (nonassortative mating).

Slouching is usually considered a bad posture habit, which many parents may be nitpicking their teens for. While it may also be just a bad sitting position, according to experts, a slouch that ...

An interdisciplinary research team led by Professor Dr. Bent Brachvogel has examined how mitochondria influence the premature ...

have been identified as major contributors to the short stature in skeletal disorders. Primordial dwarfism is a group of genetic disorders characterized by severe growth arrest that begins before ...

Patients with degenerative diseases that attack skeletal muscle tissues, such as Duchenne muscular dystrophy, may soon benefit from novel stem cell therapies. A study has demonstrated how new ...

The Outi Mäkitie research group studies genetic defects and clinical factors underlying skeletal disorders, with main interests in early-onset primary and secondary osteoporosis, skeletal dysplasias, ...

Research in the Leinwand lab focuses on unraveling mechanisms of genetic heart and skeletal muscle diseases using animal models, cell-culture systems and biophysical approaches. In addition to ...

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting cartilage metabolism. The study identified maladaptive metabolic shifts, ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.