Release of proteases from LROs into the host cell cytoplasm can trigger apoptosis unless the proteases are countered by cytoplasmic protease inhibitors. Regulated release of endolysosomal ...
Joseph Vacca, Ph.D. Executive Director, Medicinal Chemistry West Point, Merck, Pennsylvania, USA In the mid-1990s, a new class of antiviral drugs known as HIV protease inhibitors revolutionized ...
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