I hope to help change that by generating an effective mouse model that will allow us to investigate the biological effects of the small-intestinal microbiome. How will you create the mouse model?

It can take six hours for the small intestine to do its job. The nutrients are sucked from the inner surface of the small ...

The intestine is home to a complex ecosystem of microorganisms. This so-called gut microbiome plays an important role in ...

Giardiasis, caused by the protozoan Giardia intestinalis, is the leading cause of intestinal parasitic infections in humans ...

In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...

“The intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation,” Dempsey explains. “The cells dedifferentiate back into a ...

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study ...

A research team from the Medical University ... in a humanized mouse model with cells from PSC patients, which indicates that this effect could also work in the human intestine." ...

In order to increase the complexity of this human biomimetic model, we are integrating engineered ... involved in providing organoids through the Texas Medical Center Gastrointestinal Models Core.