Accordingly, the total loss of DNA ligase function is lethal. DNA ligases catalyze the joining of a 5’-phosphate-terminated strand to a 3’-hydroxyl-terminated strand. Ligation depends on magnesium and ...
Phage T4 polynucleotide kinase/phosphatase (Pnkp) and RNA ligase 1 (Rnl1) are prototypal RNA healing and sealing enzymes. They function in vivo to repair a break in E. coli tRNA Lys triggered by phage ...
Hosted on MSN2mon
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzymeThe diversity of cellular functions of ubiquitination is reflected in the existence of over 600 human E3 ligase genes, representing approximately 3% of the human genome. Mapping the human E3 ...
Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants ...
News-Medical.Net on MSN9d
Scientists find links between bipolar disorder and rare loss-of-function variants in two genesScientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback