It’s hard to imagine suddenly losing your sight in your 20s, but that’s what happened to Richard Wheeler when he developed Leber’s hereditary optic neuropathy (LHON). People with LHON ...

Lenadogene nolparvovec, an adeno-associated virus (AAV)-based gene therapy, was developed to address LHON and has been ...

The testing revealed that Christiane also carries the faulty gene. It means that both her children, Ramus, 19, and 14-year-old Katrine, are at risk of developing LHON. “Me and my family were ...

One of these mitochondria-associated disorders is Leber hereditary optic neuropathy (LHON), which leads to a ... to the likely involvement of other genes and environmental factors.

With no other effective treatment options, Neurophth is developing two gene therapy candidates for LHON. Qiutang Li’s team uses a recombinant adeno-associated virus (AAV) to deliver the correct ...