Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional ...

Further research revealed that the specific histone H3.3 chaperone HIRA interacts with both dPCIF1 and GAF in the early embryo. Maternal depletion of HIRA causes complete embryonic lethality and a ...

The teams found that TG2 acts as a regulator of intracellular monoamine neurotransmitters with an ability to not only add monoamines to histone H3 but also erase and exchange one monoamine ...