Scientists have long known that more than 500 genes (out of approximately 20,000 human protein-coding genes) are crucial for DNA repair. By comprehensively analysing the interactions of these ...

Scientists have long known that more than 500 genes (out of approximately 20,000 human protein-coding genes) are crucial for DNA repair. By comprehensively analyzing the interactions of these ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA ...

(A) Common DNA damaging agents (top), examples of ... base- and nucleotide-excision repair, respectively; HR, homologous recombination; EJ, end joining.

We know that if a DNA repair gene is mutated ... Researchers who have performed similar experiments have concluded that HR plays a main role in accomplishing this highly accurate repair ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

PARP inhibitors (PARPi) are used for the treatment of cancers with deficiencies in the homologous recombination (HR) DNA repair pathway, which can be due to defects in genes such as BRCA1, BRCA2, ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question.

DNA repair mechanisms are crucial for the survival and growth of cells. Through a comprehensive analysis, a research team at ETH Zurich has identified numerous redundancies between the genes involved ...