Her general practitioner diagnosed gouty arthritis because of a high serum uric-acid level (600 µmol/l; normal range 270–380 µmol/l) coexistent with tophi in her hands, and initiated ...

Left untreated, gout in the elbow can lead to permanent joint damage and tophi—painful bumps where uric acid crystals have ...

Gout can cause excruciating joint pain along with swelling and stiffness. Left untreated, tophi can lead to infection, skin ulceration (open sores), and neuropathy (numbness or pins-and-needles ...

MDedge News, December 15, 2022 ACR 2022 Intensive Gout Treatment Meets Urate Goal, Lowers Tophi Burden The second randomized trial of therapy to intensively lower urate for patients with gout ...

dose-ranging clinical study in refractory gout patients with or without tophi, to evaluate the efficacy and safety of a 10, 30, or 60 mg tablet dose of SAP-001. The study enrolled 87 patients from ...

and dissolve tophi in gout and tophaceous gout patients, today announced that it has dosed the first patient in REDUCE 1, the Company's second pivotal Phase 3 clinical trial evaluating AR882.

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...