This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Researchers discovered that saccharin kills drug-resistant bacteria, disrupts their DNA, and helps antibiotics work better.

Scientists have identified a key vulnerability in pancreatic cancer by targeting transcription-replication conflicts—cellular ...

Numerous widely used chemicals induce genetic and epigenetic alterations implicated in various diseases, including cancer.

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits.

Researchers have identified a new molecular target for treating pancreatic cancer. Scientists focused on transcription-replication conflicts (TRCs), which occur when the mechanisms responsible for ...

Saccharin, the artificial sweetener used in diet foods like yogurts and sugar-free drinks, can kill multidrug-resistant ...

A new study focused on transcription-replication conflicts, which occur when mechanisms responsible for gene expression and ...