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The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers led by the Leibniz Institute IPK has ...
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Centromere research yields new insights into the mechanisms of chromosome segregation errorsResearchers from the Hubrecht Institute's Kops group, in collaboration with researchers from the University of Edinburgh, have made a surprising new discovery in the structure of the centromere ...
virginiana and F. chiloensis. However, the differences in centromere characteristics and evolutionary patterns between wild and cultivated octoploids have remained poorly understood. In a study ...
With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...
The pairs of chromosomes that have been replicated are called sister chromatids, and they remain joined at a central point called the centromere. A large structure called the mitotic spindle also ...
To convert a piece of cloned DNA into a centromere-containing human artificial chromosome (HAC), an array of repeated LacO sequences is incorporated into the DNA. The DNA is then transfected into ...
with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains (arrowheads).
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