He looked at why engineered CAR Tregs, which in theory should function the same as natural ... The CAR, or chimeric antigen receptor, recognizes and homes in on a specific antigen on the surface ...

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

Beyond that, we have a particular interest in the biological and enzymatic function of PSMA as it pertains to tumor ... Targeting the internal epitope of prostate-specific membrane antigen with 89 ...

Experiments have shown that it functions like a dedicated “courier”, capable of accurately and effectively delivering antigens from the cytoplasm to the endoplasmic reticulum.