Microtubules are the largest type of filament, with a diameter of about 25 nanometers (nm), and they are composed of a protein called tubulin. Actin filaments are the smallest type, with a ...

Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...

An individual sarcomere contains many parallel actin (thin) and myosin (thick) filaments. The interaction of myosin and actin proteins is at the core of our current understanding of sarcomere ...

Alushin's lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell's infrastructure. Actin serves many functions: it provides cells ...

The forces at work Alushin’s lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell’s infrastructure. Actin serves many ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Intrigued, Tilney took on the project, and together the pair showed that after breaking out of the vacuole, Listeria managed, somehow, to construct its own tail-like structure out of actin filaments. ...

it uses a protein called ActA to recruit the host cell’s actin polymerization machinery to construct a tail of actin filaments behind it (3). This process gives the bacterium a means to propel itself ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

The organization and dynamics of actin filaments must be precisely controlled during these processes, and consequently defects in regulation of the actin cytoskeleton lead to various diseases ...