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Unlike actin filaments and microtubules, intermediate filaments are constructed from a number of different subunit proteins. Microtubules tend to grow out from the centrosome to the plasma membrane.
The role of centrosomal tubulin glutamylation has remained elusive for decades. Here, a new tool enables precise spatiotemporal control of this modification, showing that it physically recruits ...
a component of the actin-related protein 2/3 (ARP2/3) complex, binds and activates Aurora A and is a novel regulator of centrosome integrity. the cytoskeletal remodelling protein ARPC1B ...
During synapse formation, these granules coalesce around the CTL centrosome, which reorients to a position just beneath the cell-cell contact. Concomitantly, filamentous actin at the interface is ...